Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Cryo-electron microscopy (cryo-EM) has become a leading technology for determining protein structures. Recent advances in this field have allowed for atomic resolution. However, predicting the backbone trace of a protein has remained a challenge on all but the most pristine density maps (<2.5 Å r...

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Detalles Bibliográficos
Autores principales: Si, Dong, Moritz, Spencer A., Pfab, Jonas, Hou, Jie, Cao, Renzhi, Wang, Liguo, Wu, Tianqi, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063051/
https://www.ncbi.nlm.nih.gov/pubmed/32152330
http://dx.doi.org/10.1038/s41598-020-60598-y

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