Cargando…
Platelets in Amyloidogenic Mice Are Activated and Invade the Brain
Alzheimer’s disease (AD) is a neurodegenerative disease with a complex and not fully understood pathogenesis. Besides brain-intrinsic hallmarks such as abnormal deposition of harmful proteins, i.e., amyloid beta in plaques and hyperphosphorylated Tau in neurofibrillary tangles, blood-derived element...
Autores principales: | Kniewallner, Kathrin M., de Sousa, Diana M. Bessa, Unger, Michael S., Mrowetz, Heike, Aigner, Ludwig |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063083/ https://www.ncbi.nlm.nih.gov/pubmed/32194368 http://dx.doi.org/10.3389/fnins.2020.00129 |
Ejemplares similares
-
Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice
por: de Sousa, Diana M. Bessa, et al.
Publicado: (2023) -
TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?
por: Kandasamy, Mahesh, et al.
Publicado: (2020) -
The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study
por: de Sousa, Diana M. Bessa, et al.
Publicado: (2023) -
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus
por: Klein, Barbara, et al.
Publicado: (2016) -
Age Influences Microglial Activation After Cuprizone-Induced Demyelination
por: Klein, Barbara, et al.
Publicado: (2018)