Cargando…

Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis

To support great demand of cell growth, cancer cells preferentially obtain energy and biomacromolecules by glycolysis over mitochondrial oxidative phosphorylation (OxPhos). Among all glycolytic enzymes, hexokinase (HK), a rate-limiting enzyme at the first step of glycolysis to catalyze cellular gluc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wan-Chun, Huang, Chien-Hsiang, Hsieh, Yi-Ta, Chen, Tsai-Ying, Cheng, Li-Hao, Chen, Chang-Yi, Liu, Chung-Ji, Chen, Hsin-Ming, Huang, Chien-Ling, Lo, Jeng-Fan, Chang, Kuo-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063098/ https://www.ncbi.nlm.nih.gov/pubmed/32195170 http://dx.doi.org/10.3389/fonc.2020.00176

Ejemplares similares

Corrigendum: Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis
por: Li, Wan-Chun, et al.
Publicado: (2020)

Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis()
por: Chen, Tsai-Ying, et al.
Publicado: (2019)

Targeting Cellular Metabolism Modulates Head and Neck Oncogenesis
por: Hsieh, Yi-Ta, et al.
Publicado: (2019)

Gastrointestinal Endoscopy Performed by Gastroenterologists: Opportunistic Screening Strategy for Newly Diagnosed Head and Neck Cancers
por: Yang, Chih-Wei, et al.
Publicado: (2022)

Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors
por: Hsieh, Yi-Ta, et al.
Publicado: (2021)

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis
por: Zhang, Jia, et al.
Publicado: (2017)

MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma
por: Chen, Li-Hsin, et al.
Publicado: (2010)

DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis
por: Huang, Tai‐Lin, et al.
Publicado: (2022)

High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area
por: Chiu, Tai-Jan, et al.
Publicado: (2011)

Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ
por: Cai, Jing, et al.
Publicado: (2021)

Prognostic Value of C-Reactive Protein-to-Albumin Ratio in Head and Neck Cancer: A Meta-Analysis
por: Luan, Chih-Wei, et al.
Publicado: (2021)

Efficacy of the Geriatric Nutritional Risk Index for Predicting Overall Survival in Patients with Head and Neck Cancer: A Meta-Analysis
por: Yiu, Ching-Yi, et al.
Publicado: (2023)

Correction to: Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ
por: Cai, Jing, et al.
Publicado: (2021)

Lyophilized particles and ethanolic extracts of Antrodia cinnamomea mycelia suppress the tumorigenicity of head and neck cancer cells in vivo
por: Chang, Ching-Wen, et al.
Publicado: (2014)

Abstract: Postoperative Hematoma in Microvascular Reconstruction of the Head and Neck
por: Chang, Dun Hao, et al.
Publicado: (2017)

Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers
por: Kanno, Yuzuka, et al.
Publicado: (2021)

Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer
por: Lai, Chien-Hsien, et al.
Publicado: (2017)

Dynamic cellular and molecular modulations of diabetes mediated head and neck carcinogenesis
por: Liu, Chung-Ji, et al.
Publicado: (2015)

Traditional Herbal Medicine Mediated Regulations during Head and Neck Carcinogenesis
por: Lan, Xiang-Yun, et al.
Publicado: (2020)

Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer
por: Chen, Chang-Han, et al.
Publicado: (2015)

The Sonography and Physical Findings on Shoulder after Selective Neck Dissection in Patients with Head and Neck Cancer: A Pilot Study
por: Huang, Yu-Chi, et al.
Publicado: (2019)

Tea Consumption and Risk of Head and Neck Cancer
por: Huang, Cheng-Chih, et al.
Publicado: (2014)

Aspirin associated with risk reduction of secondary primary cancer for patients with head and neck cancer: A population-based analysis
por: Lin, Yu-Shan, et al.
Publicado: (2018)

Deciphering the Functions of Telomerase Reverse Transcriptase in Head and Neck Cancer
por: Yeh, Tsung-Jang, et al.
Publicado: (2023)

Artificial neural network approach to predict surgical site infection after free-flap reconstruction in patients receiving surgery for head and neck cancer
por: Kuo, Pao-Jen, et al.
Publicado: (2018)

SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis
por: Shangguan, Xun, et al.
Publicado: (2021)

Evaluation of Objective and Subjective Swallowing Outcomes in Patients with Dysphagia Treated for Head and Neck Cancer
por: Liou, Hsin-Hao, et al.
Publicado: (2022)

The cylindromatosis (CYLD) gene and head and neck tumorigenesis
por: Verhoeft, Krista Roberta, et al.
Publicado: (2016)

Role of Cyclooxygenase-2 in Head and Neck Tumorigenesis
por: Frejborg, Ellen, et al.
Publicado: (2020)

Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers
por: Cheng, Li-Hao, et al.
Publicado: (2016)

Dehydroepiandrosterone (DHEA) Sensitizes Irinotecan to Suppress Head and Neck Cancer Stem-Like Cells by Downregulation of WNT Signaling
por: Li, Li-Jie, et al.
Publicado: (2022)

Downregulation of ATM and BRCA1 Predicts Poor Outcome in Head and Neck Cancer: Implications for ATM-Targeted Therapy
por: Wang, Yu-Chu, et al.
Publicado: (2021)

Insonation of Systemically Delivered Cisplatin-Loaded Microbubbles Significantly Attenuates Nephrotoxicity of Chemotherapy in Experimental Models of Head and Neck Cancer
por: Chen, Hang-Kang, et al.
Publicado: (2018)

Persistently elevated soluble MHC class I polypeptide-related sequence A and transforming growth factor-β1 levels are poor prognostic factors in head and neck squamous cell carcinoma after definitive chemoradiotherapy
por: Chen, Jenny Ling-Yu, et al.
Publicado: (2018)

Hypothyroidism and risks of cerebrovascular complications among patients with head and neck cancer after radiotherapy
por: Liu, Chi-Hung, et al.
Publicado: (2021)

Regular recreational physical activity and risk of head and neck cancer
por: Lin, Chen-Lin, et al.
Publicado: (2017)

UBE2C triggers HIF‐1α‐glycolytic flux in head and neck squamous cell carcinoma
por: Yang, Yi‐Fang, et al.
Publicado: (2022)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death
por: Chang, Ching-Wen, et al.
Publicado: (2013)

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior
por: Chien, Chih-Yen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8vg4tf8hh7lm6m9qv71vabvrl1