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Medical Reversals in Family Practice: A Review
BACKGROUND: Primary care physicians are challenged by the need to stay abreast of current research on a wide variety of topics in an environment of time constraints, evolving literature, and misinformation on health topics that are sometimes promulgated to the public. OBJECTIVE: We sought to identif...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063107/ https://www.ncbi.nlm.nih.gov/pubmed/32180846 http://dx.doi.org/10.1016/j.curtheres.2020.100579 |
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author | Haslam, Alyson Livingston, Catherine Prasad, Vinay |
author_facet | Haslam, Alyson Livingston, Catherine Prasad, Vinay |
author_sort | Haslam, Alyson |
collection | PubMed |
description | BACKGROUND: Primary care physicians are challenged by the need to stay abreast of current research on a wide variety of topics in an environment of time constraints, evolving literature, and misinformation on health topics that are sometimes promulgated to the public. OBJECTIVE: We sought to identify and discuss common clinical situations encountered in primary care for which medical reversals have occurred. METHODS: We recently identified almost 400 medical practices that were used in clinical care before they were tested in well-done randomized controlled trials and subsequently were found to be ineffective or harmful. RESULTS: We review several of these practices commonly used in family medicine, which include arthroscopy for osteoarthritis of the knee, opioids for common causes of pain, and aspirin and continuous positive airway pressure for the prevention of cardiovascular disease. CONCLUSIONS: Although these practices were implemented because of sound biologic plausibility or encouraging observational data, well done randomized controlled trials have failed to show evidence of effectiveness. These examples raise caution in introducing new clinical interventions into widespread clinical practice without sufficient high-quality evidence demonstrating efficacy. |
format | Online Article Text |
id | pubmed-7063107 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70631072020-03-16 Medical Reversals in Family Practice: A Review Haslam, Alyson Livingston, Catherine Prasad, Vinay Curr Ther Res Clin Exp Original Research BACKGROUND: Primary care physicians are challenged by the need to stay abreast of current research on a wide variety of topics in an environment of time constraints, evolving literature, and misinformation on health topics that are sometimes promulgated to the public. OBJECTIVE: We sought to identify and discuss common clinical situations encountered in primary care for which medical reversals have occurred. METHODS: We recently identified almost 400 medical practices that were used in clinical care before they were tested in well-done randomized controlled trials and subsequently were found to be ineffective or harmful. RESULTS: We review several of these practices commonly used in family medicine, which include arthroscopy for osteoarthritis of the knee, opioids for common causes of pain, and aspirin and continuous positive airway pressure for the prevention of cardiovascular disease. CONCLUSIONS: Although these practices were implemented because of sound biologic plausibility or encouraging observational data, well done randomized controlled trials have failed to show evidence of effectiveness. These examples raise caution in introducing new clinical interventions into widespread clinical practice without sufficient high-quality evidence demonstrating efficacy. Elsevier 2020-02-22 /pmc/articles/PMC7063107/ /pubmed/32180846 http://dx.doi.org/10.1016/j.curtheres.2020.100579 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Haslam, Alyson Livingston, Catherine Prasad, Vinay Medical Reversals in Family Practice: A Review |
title | Medical Reversals in Family Practice: A Review |
title_full | Medical Reversals in Family Practice: A Review |
title_fullStr | Medical Reversals in Family Practice: A Review |
title_full_unstemmed | Medical Reversals in Family Practice: A Review |
title_short | Medical Reversals in Family Practice: A Review |
title_sort | medical reversals in family practice: a review |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063107/ https://www.ncbi.nlm.nih.gov/pubmed/32180846 http://dx.doi.org/10.1016/j.curtheres.2020.100579 |
work_keys_str_mv | AT haslamalyson medicalreversalsinfamilypracticeareview AT livingstoncatherine medicalreversalsinfamilypracticeareview AT prasadvinay medicalreversalsinfamilypracticeareview |