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Ca(2+) signaling in T lymphocytes: the interplay of the endoplasmic reticulum, mitochondria, membrane potential, and CRAC channels on transcription factor activation
T cell receptor stimulation initiates a cascade of reactions that cause an increase in intracellular calcium (Ca(2+)) concentration mediated through inositol 1,4,5-trisphosphate (IP(3)). To understand the basic mechanisms by which the immune response in T cells is activated, it is useful to understa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063158/ https://www.ncbi.nlm.nih.gov/pubmed/32181396 http://dx.doi.org/10.1016/j.heliyon.2020.e03526 |