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Local Drug Delivery to the Entire Cochlea without Breaching Its Boundaries
The mammalian cochlea is one of the least accessible organs for drug delivery. Systemic administration of many drugs is severely limited by the blood-labyrinth barrier. Local intratympanic administration into the middle ear would be a preferable option in this case, and the only option for many newl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063177/ https://www.ncbi.nlm.nih.gov/pubmed/32151971 http://dx.doi.org/10.1016/j.isci.2020.100945 |