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Engineered Biosynthesis of Alkyne-Tagged Polyketides by Type I PKSs

Polyketides produced by modular polyketide synthases (PKSs) are important small molecules widely used as drugs, pesticides, and biological probes. Tagging these polyketides with a clickable functionality enables the visualization, diversification, and mode of action study through bio-orthogonal chem...

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Detalles Bibliográficos
Autores principales:	Porterfield, William B., Poenateetai, Nannalin, Zhang, Wenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063234/ https://www.ncbi.nlm.nih.gov/pubmed/32146323 http://dx.doi.org/10.1016/j.isci.2020.100938

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