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Class C CpG Oligodeoxynucleotide Immunomodulatory Response in Aged Squirrel Monkey (Saimiri Boliviensis Boliviensis)
One means of stimulating the mammalian innate immune system is via Toll-like receptor 9 (TLR9) being exposed to unmethylated cytosine-phosphate-guanine (CpG) DNA, also known as pathogen-associated molecular patterns (PAMPs) of microbial origin. Synthetic CpG oligodeoxynucleotides (ODNs) with defined...
Autores principales: | Nehete, Pramod N., Williams, Lawrence E., Chitta, Sriram, Nehete, Bharti P., Patel, Akash G., Ramani, Margish D., Wisniewski, Thomas, Scholtzova, Henrieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063459/ https://www.ncbi.nlm.nih.gov/pubmed/32194391 http://dx.doi.org/10.3389/fnagi.2020.00036 |
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