The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis

The cyclin-dependent kinases (CDKs) are the major cell-cycle regulators that phosphorylate hundreds of substrates, controlling the onset of S phase and M phase [1, 2, 3]. However, the patterns of substrate phosphorylation increase are not uniform, as different substrates become phosphorylated at dif...

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Detalles Bibliográficos
Autores principales: Basu, Souradeep, Roberts, Emma L., Jones, Andrew W., Swaffer, Matthew P., Snijders, Ambrosius P., Nurse, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063568/
https://www.ncbi.nlm.nih.gov/pubmed/32084401
http://dx.doi.org/10.1016/j.cub.2019.12.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063568/
https://www.ncbi.nlm.nih.gov/pubmed/32084401
http://dx.doi.org/10.1016/j.cub.2019.12.053

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