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Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators
The ability to identify single-nucleotide mutations is critical for probing cell biology and for precise detection of disease. However, the small differences in hybridization energy provided by single-base changes makes identification of these mutations challenging in living cells and complex reacti...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063572/ https://www.ncbi.nlm.nih.gov/pubmed/32109416 http://dx.doi.org/10.1016/j.cell.2020.02.011 |