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Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis
Eosinophilic infiltration is a rare and underrecognized cause of myocarditis associated with prolonged eosinophilia. Before advanced imaging and routine biopsy, patients were diagnosed with an idiopathic cardiomyopathy with subsequent diagnosis made on autopsy. We present 3 cases of eosinophilic myo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063606/ https://www.ncbi.nlm.nih.gov/pubmed/32159090 http://dx.doi.org/10.1016/j.cjco.2019.01.001 |
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author | Chiu, Michael H. Sharma, Nakul C. |
author_facet | Chiu, Michael H. Sharma, Nakul C. |
author_sort | Chiu, Michael H. |
collection | PubMed |
description | Eosinophilic infiltration is a rare and underrecognized cause of myocarditis associated with prolonged eosinophilia. Before advanced imaging and routine biopsy, patients were diagnosed with an idiopathic cardiomyopathy with subsequent diagnosis made on autopsy. We present 3 cases of eosinophilic myocarditis diagnosed by cardiac biopsy classified as hypereosinophilic syndrome. Two patients presented with severe left ventricular dysfunction, and 1 patient presented with cardioembolic stroke. All patients were successfully treated with glucocorticoid therapy. Our cases highlight the importance of early diagnosis with endomyocardial biopsy and prompt immunosuppressive treatment. |
format | Online Article Text |
id | pubmed-7063606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70636062020-03-10 Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis Chiu, Michael H. Sharma, Nakul C. CJC Open Case Report Eosinophilic infiltration is a rare and underrecognized cause of myocarditis associated with prolonged eosinophilia. Before advanced imaging and routine biopsy, patients were diagnosed with an idiopathic cardiomyopathy with subsequent diagnosis made on autopsy. We present 3 cases of eosinophilic myocarditis diagnosed by cardiac biopsy classified as hypereosinophilic syndrome. Two patients presented with severe left ventricular dysfunction, and 1 patient presented with cardioembolic stroke. All patients were successfully treated with glucocorticoid therapy. Our cases highlight the importance of early diagnosis with endomyocardial biopsy and prompt immunosuppressive treatment. Elsevier 2019-03-29 /pmc/articles/PMC7063606/ /pubmed/32159090 http://dx.doi.org/10.1016/j.cjco.2019.01.001 Text en © 2019 Canadian Cardiovascular Society. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Chiu, Michael H. Sharma, Nakul C. Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title | Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title_full | Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title_fullStr | Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title_full_unstemmed | Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title_short | Myocarditis and Eosinophilia: Three Cases of Hypereosinophilic Syndrome and Myocarditis |
title_sort | myocarditis and eosinophilia: three cases of hypereosinophilic syndrome and myocarditis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063606/ https://www.ncbi.nlm.nih.gov/pubmed/32159090 http://dx.doi.org/10.1016/j.cjco.2019.01.001 |
work_keys_str_mv | AT chiumichaelh myocarditisandeosinophiliathreecasesofhypereosinophilicsyndromeandmyocarditis AT sharmanakulc myocarditisandeosinophiliathreecasesofhypereosinophilicsyndromeandmyocarditis |