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Efficacy of Evolocumab in Monogenic vs Polygenic Hypercholesterolemia
BACKGROUND: Inhibitors of proprotein convertase subtilisin kexin 9 are indicated in Canada for treatment of patients with familial hypercholesterolemia (FH). Classically, FH is considered to be a monogenic condition caused by rare pathogenic mutations; however, some patients have hypercholesterolemi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063626/ https://www.ncbi.nlm.nih.gov/pubmed/32159093 http://dx.doi.org/10.1016/j.cjco.2019.02.005 |