Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach

BACKGROUND: B cell receptor Immunoglobulin (BcR IG) repertoire of Chronic Lymphocytic Leukemia (CLL) is characterized by the expression of quasi-identical BcR IG. These are observed in approximately 30% of patients, defined as stereotyped receptors and subdivided into subsets based on specific VH CD...

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Detalles Bibliográficos
Autores principales: Colombo, Monica, Bagnara, Davide, Reverberi, Daniele, Matis, Serena, Cardillo, Martina, Massara, Rosanna, Mastracci, Luca, Ravetti, Jean Louis, Agnelli, Luca, Neri, Antonino, Mazzocco, Michela, Squillario, Margherita, Mazzarello, Andrea Nicola, Cutrona, Giovanna, Agathangelidis, Andreas, Stamatopoulos, Kostas, Ferrarini, Manlio, Fais, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063734/
https://www.ncbi.nlm.nih.gov/pubmed/32156260
http://dx.doi.org/10.1186/s10020-020-00151-9

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