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High-resolution modeling of the selection on local mRNA folding strength in coding sequences across the tree of life

BACKGROUND: mRNA can form local secondary structure within the protein-coding sequence, and the strength of this structure is thought to influence gene expression regulation. Previous studies suggest that secondary structure strength may be maintained under selection, but the details of this phenome...

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Detalles Bibliográficos
Autores principales:	Peeri, Michael, Tuller, Tamir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063772/ https://www.ncbi.nlm.nih.gov/pubmed/32151272 http://dx.doi.org/10.1186/s13059-020-01971-y

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