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Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo

BACKGROUND: Tamoxifen (TAM) is a cell type-specific anti-estrogen and is applied to improve the survival of patients with estrogen receptor positive (ER +) breast cancer. However, long-term TAM use can induce serious drug resistance, leading to breast cancer recurrence and death in patients. Further...

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Detalles Bibliográficos
Autores principales:	Lin, Hong-Yan, Han, Hong-Wei, Wang, Yin-Song, He, De-Liu, Sun, Wen-Xue, Feng, Lu, Wen, Zhong-Ling, Yang, Min-Kai, Lu, Gui-Hua, Wang, Xiao-Ming, Qi, Jin-Liang, Yang, Yong-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063777/ https://www.ncbi.nlm.nih.gov/pubmed/32175001 http://dx.doi.org/10.1186/s13020-020-00305-1

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