Cargando…
Blunted Vagal Cocaine- and Amphetamine-Regulated Transcript Promotes Hyperphagia and Weight Gain
The vagus nerve conveys gastrointestinal cues to the brain to control eating behavior. In obesity, vagally mediated gut-brain signaling is disrupted. Here, we show that the cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide synthesized proportional to the food consumed in vagal a...
Autores principales: | Lee, Shin J., Krieger, Jean-Philippe, Vergara, Macarena, Quinn, Danielle, McDougle, Molly, de Araujo, Alan, Darling, Rebecca, Zollinger, Benjamin, Anderson, Seth, Pan, Annabeth, Simonnet, Emilie J., Pignalosa, Angelica, Arnold, Myrtha, Singh, Arashdeep, Langhans, Wolfgang, Raybould, Helen E., de Lartigue, Guillaume |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063787/ https://www.ncbi.nlm.nih.gov/pubmed/32049029 http://dx.doi.org/10.1016/j.celrep.2020.01.045 |
Ejemplares similares
-
Intact vagal gut‐brain signalling prevents hyperphagia and excessive weight gain in response to high‐fat high‐sugar diet
por: McDougle, Molly, et al.
Publicado: (2020) -
Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity
por: de Lartigue, Guillaume, et al.
Publicado: (2014) -
Asymmetric control of food intake by left and right vagal sensory neurons
por: de Araujo, Alan Moreira, et al.
Publicado: (2023) -
Vagal plasticity the key to obesity
por: de Lartigue, Guillaume, et al.
Publicado: (2014) -
Levels of Cocaine- and Amphetamine-Regulated Transcript in Vagal Afferents in the Mouse Are Unaltered in Response to Metabolic Challenges
por: Yuan, Xuefeng, et al.
Publicado: (2016)