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Circulating Gasdermin-D in Critically Ill Patients
The key to further improving outcomes in sepsis lies in understanding and abrogating the dysfunctional immune response that leads to organ failure. Activation of gasdermin-D, a pore-forming protein within the inflammasome cascade, has recently been recognized as the critical step in pyroptosis and o...
Autores principales: | Homsy, Elie, Das, Srabani, Consiglio, Paul, McAtee, Corynn, Zachman, Angela, Nagaraja, Haikady, Wewers, Mark D., Exline, Matthew C., Mallampalli, Rama K., Sarkar, Anasuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063936/ https://www.ncbi.nlm.nih.gov/pubmed/32166281 http://dx.doi.org/10.1097/CCE.0000000000000039 |
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