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Staphylococcus Toxin-Mediated Motor Polyneuropathy
Staphylococcus aureus infection is known to cause a variety of neurologic complications, most involving the CNS, however, rarely have cases of S. aureus affecting the peripheral nervous system been reported in literature. We report a case of S. aureus toxin-mediated motor polyneuropathy in a patient...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063940/ https://www.ncbi.nlm.nih.gov/pubmed/32166283 http://dx.doi.org/10.1097/CCE.0000000000000041 |
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author | Pervaiz, Abdullah M. Akhtar, Raheel Mercado, Melissa |
author_facet | Pervaiz, Abdullah M. Akhtar, Raheel Mercado, Melissa |
author_sort | Pervaiz, Abdullah M. |
collection | PubMed |
description | Staphylococcus aureus infection is known to cause a variety of neurologic complications, most involving the CNS, however, rarely have cases of S. aureus affecting the peripheral nervous system been reported in literature. We report a case of S. aureus toxin-mediated motor polyneuropathy in a patient presenting with acute flaccid quadriplegia. CASE SUMMARY: A 64-year-old female with mantle cell lymphoma on oral chemotherapy with ibrutinib presents with malaise and progressive ascending bilateral lower extremity weakness. Blood cultures resulted positive for methicillin-sensitive S. aureus, and she was initiated on antibiotics. Imaging studies and laboratory workup were negative for other causes of acute flaccid quadriplegia. Patient had complete resolution of her neurologic deficits with antibiotic therapy. It was determined that the likely diagnosis was Staphylococcus toxin-mediated motor polyneuropathy. CONCLUSIONS: Staphylococcal-mediated motor polyneuropathy resulting in acute flaccid quadriplegia is a rare but treatable complication of bacteremia and should remain a diagnosis of exclusion. |
format | Online Article Text |
id | pubmed-7063940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-70639402020-03-12 Staphylococcus Toxin-Mediated Motor Polyneuropathy Pervaiz, Abdullah M. Akhtar, Raheel Mercado, Melissa Crit Care Explor Case Report Staphylococcus aureus infection is known to cause a variety of neurologic complications, most involving the CNS, however, rarely have cases of S. aureus affecting the peripheral nervous system been reported in literature. We report a case of S. aureus toxin-mediated motor polyneuropathy in a patient presenting with acute flaccid quadriplegia. CASE SUMMARY: A 64-year-old female with mantle cell lymphoma on oral chemotherapy with ibrutinib presents with malaise and progressive ascending bilateral lower extremity weakness. Blood cultures resulted positive for methicillin-sensitive S. aureus, and she was initiated on antibiotics. Imaging studies and laboratory workup were negative for other causes of acute flaccid quadriplegia. Patient had complete resolution of her neurologic deficits with antibiotic therapy. It was determined that the likely diagnosis was Staphylococcus toxin-mediated motor polyneuropathy. CONCLUSIONS: Staphylococcal-mediated motor polyneuropathy resulting in acute flaccid quadriplegia is a rare but treatable complication of bacteremia and should remain a diagnosis of exclusion. Wolters Kluwer Health 2019-09-04 /pmc/articles/PMC7063940/ /pubmed/32166283 http://dx.doi.org/10.1097/CCE.0000000000000041 Text en Copyright © 2019 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Case Report Pervaiz, Abdullah M. Akhtar, Raheel Mercado, Melissa Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title | Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title_full | Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title_fullStr | Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title_full_unstemmed | Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title_short | Staphylococcus Toxin-Mediated Motor Polyneuropathy |
title_sort | staphylococcus toxin-mediated motor polyneuropathy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063940/ https://www.ncbi.nlm.nih.gov/pubmed/32166283 http://dx.doi.org/10.1097/CCE.0000000000000041 |
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