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Impact of Inaccurate Documentation of Sampling and Infusion Time in Model-Informed Precision Dosing

BACKGROUND: Routine clinical TDM data is often used to develop population pharmacokinetic (PK) models, which are applied in turn for model-informed precision dosing. The impact of uncertainty in documented sampling and infusion times in population PK modeling and model-informed precision dosing have...

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Detalles Bibliográficos
Autores principales:	Alihodzic, Dzenefa, Broeker, Astrid, Baehr, Michael, Kluge, Stefan, Langebrake, Claudia, Wicha, Sebastian Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063976/ https://www.ncbi.nlm.nih.gov/pubmed/32194411 http://dx.doi.org/10.3389/fphar.2020.00172

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