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The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions
PURPOSE: To evaluate the ability and the utility of diffusion-weighted magnetic resonance imaging (MRI) with different ‘b’ values to visualise benign and malignant lung lesions, and to determine which ‘b’ value (b = 300, 500, or 1000 s/mm(2)) was most useful in differentiating benign from malignant...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064016/ https://www.ncbi.nlm.nih.gov/pubmed/32180849 http://dx.doi.org/10.5114/pjr.2020.92834 |
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author | Elbir, Şenol Fatih Öztürk, Mehmet Doğan, Serap |
author_facet | Elbir, Şenol Fatih Öztürk, Mehmet Doğan, Serap |
author_sort | Elbir, Şenol Fatih |
collection | PubMed |
description | PURPOSE: To evaluate the ability and the utility of diffusion-weighted magnetic resonance imaging (MRI) with different ‘b’ values to visualise benign and malignant lung lesions, and to determine which ‘b’ value (b = 300, 500, or 1000 s/mm(2)) was most useful in differentiating benign from malignant lung lesions. MATERIAL AND METHODS: A total of 100 patients (28 women, 72 men; mean age = 57.19 ± 13.44 years; age range = 20-83 years). Diffusion-weighted imaging (DWI) was obtained with ‘b’ values of 300, 500, and 1000 s/mm(2). The signal intensity of lesions on DWI images was analysed, and the apparent diffusion coefficient (ADC) values of the lesions were calculated. MRI was performed in all patients after having presented at our department for thoracic computed tomography for various reasons. RESULTS: A statistically significant difference in DWI signal scores was detected between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). The sensitivity and specificity were 95% and 64%, respectively, when a score of 3 for β = 300 s/mm(2); 90% and 69%, respectively, when a score of 3 for β = 500 s/mm(2); and 84% and 74%, respectively, when a score of 3 for β = 1000 s/mm(2). ADC values showed significant differences between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). CONCLUSIONS: Using ‘b’ values of 300, 500, and 1000 s/mm(2), DWI signal intensity scores and ADC values are effective methods for the differential diagnosis of malignant and benign pulmonary lesions. |
format | Online Article Text |
id | pubmed-7064016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-70640162020-03-16 The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions Elbir, Şenol Fatih Öztürk, Mehmet Doğan, Serap Pol J Radiol Original Paper PURPOSE: To evaluate the ability and the utility of diffusion-weighted magnetic resonance imaging (MRI) with different ‘b’ values to visualise benign and malignant lung lesions, and to determine which ‘b’ value (b = 300, 500, or 1000 s/mm(2)) was most useful in differentiating benign from malignant lung lesions. MATERIAL AND METHODS: A total of 100 patients (28 women, 72 men; mean age = 57.19 ± 13.44 years; age range = 20-83 years). Diffusion-weighted imaging (DWI) was obtained with ‘b’ values of 300, 500, and 1000 s/mm(2). The signal intensity of lesions on DWI images was analysed, and the apparent diffusion coefficient (ADC) values of the lesions were calculated. MRI was performed in all patients after having presented at our department for thoracic computed tomography for various reasons. RESULTS: A statistically significant difference in DWI signal scores was detected between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). The sensitivity and specificity were 95% and 64%, respectively, when a score of 3 for β = 300 s/mm(2); 90% and 69%, respectively, when a score of 3 for β = 500 s/mm(2); and 84% and 74%, respectively, when a score of 3 for β = 1000 s/mm(2). ADC values showed significant differences between benign and malignant lesions for all ‘b’ factors (p < 0.0001 for each). CONCLUSIONS: Using ‘b’ values of 300, 500, and 1000 s/mm(2), DWI signal intensity scores and ADC values are effective methods for the differential diagnosis of malignant and benign pulmonary lesions. Termedia Publishing House 2020-01-10 /pmc/articles/PMC7064016/ /pubmed/32180849 http://dx.doi.org/10.5114/pjr.2020.92834 Text en Copyright © Polish Medical Society of Radiology 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License allowing third parties to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially. |
spellingShingle | Original Paper Elbir, Şenol Fatih Öztürk, Mehmet Doğan, Serap The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title | The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title_full | The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title_fullStr | The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title_full_unstemmed | The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title_short | The ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
title_sort | ability and utility of diffusion-weighted magnetic resonance imaging with different ‘b’ values in the differentiation of benign from malignant lung lesions |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064016/ https://www.ncbi.nlm.nih.gov/pubmed/32180849 http://dx.doi.org/10.5114/pjr.2020.92834 |
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