Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions

BACKGROUND: Cutaneous lupus erythematosus (CLE) is an interferon (IFN) -driven autoimmune skin disease characterized by an extensive cytotoxic lesional inflammation with activation of different innate immune pathways. Aim of our study was to investigate the specific role of Janus kinase 1 (JAK1) act...

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Detalles Bibliográficos
Autores principales: Fetter, Tanja, Smith, Paul, Guel, Tugce, Braegelmann, Christine, Bieber, Thomas, Wenzel, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064060/
https://www.ncbi.nlm.nih.gov/pubmed/32194562
http://dx.doi.org/10.3389/fimmu.2020.00344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064060/
https://www.ncbi.nlm.nih.gov/pubmed/32194562
http://dx.doi.org/10.3389/fimmu.2020.00344

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