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Selective Janus Kinase 1 Inhibition Is a Promising Therapeutic Approach for Lupus Erythematosus Skin Lesions
BACKGROUND: Cutaneous lupus erythematosus (CLE) is an interferon (IFN) -driven autoimmune skin disease characterized by an extensive cytotoxic lesional inflammation with activation of different innate immune pathways. Aim of our study was to investigate the specific role of Janus kinase 1 (JAK1) act...
Autores principales: | Fetter, Tanja, Smith, Paul, Guel, Tugce, Braegelmann, Christine, Bieber, Thomas, Wenzel, Joerg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064060/ https://www.ncbi.nlm.nih.gov/pubmed/32194562 http://dx.doi.org/10.3389/fimmu.2020.00344 |
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