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Data‐driven analysis of JAK2V617F kinetics during interferon‐alpha2 treatment of patients with polycythemia vera and related neoplasms

Treatment with PEGylated interferon‐alpha2 (IFN) of patients with essential thrombocythemia and polycythemia vera induces major molecular remissions with a reduction in the JAK2V617F allele burden to undetectable levels in a subset of patients. A favorable response to IFN has been argued to depend u...

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Detalles Bibliográficos
Autores principales: Pedersen, Rasmus K., Andersen, Morten, Knudsen, Trine A., Sajid, Zamra, Gudmand‐Hoeyer, Johanne, Dam, Marc J. B., Skov, Vibe, Kjær, Lasse, Ellervik, Christina, Larsen, Thomas S., Hansen, Dennis, Pallisgaard, Niels, Hasselbalch, Hans C., Ottesen, Johnny T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064092/
https://www.ncbi.nlm.nih.gov/pubmed/31991066
http://dx.doi.org/10.1002/cam4.2741