Cargando…

Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China

BACKGROUND: Both hepatitis B virus (HBV) infection and schistosomiasis are important public health problems in China. Concurrent infection between HBV and schistosomiasis is often observed in areas where schistosomiasis is endemic. The aim of this study was to determine the prevalence of schistosomi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yupeng, Xie, Yaofei, Chen, Qi, Chen, Xuyu, Dong, Zhuangzhuang, Tan, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064163/
https://www.ncbi.nlm.nih.gov/pubmed/31722017
http://dx.doi.org/10.1093/trstmh/trz086
_version_ 1783504826774061056
author Zhang, Yupeng
Xie, Yaofei
Chen, Qi
Chen, Xuyu
Dong, Zhuangzhuang
Tan, Xiaodong
author_facet Zhang, Yupeng
Xie, Yaofei
Chen, Qi
Chen, Xuyu
Dong, Zhuangzhuang
Tan, Xiaodong
author_sort Zhang, Yupeng
collection PubMed
description BACKGROUND: Both hepatitis B virus (HBV) infection and schistosomiasis are important public health problems in China. Concurrent infection between HBV and schistosomiasis is often observed in areas where schistosomiasis is endemic. The aim of this study was to determine the prevalence of schistosomiasis and HBV in schistosomiasis-affected areas, to explore whether schistosomiasis patients are more susceptible to HBV and to determine if the prevalence of HBV in high-endemic areas of schistosomiasis is higher than in low-endemic areas. METHODS: A total of 6526 participants from 13 villages in Hubei province were included in a cross-sectional study and blood samples were collected and examined. Qualitative variables were compared between groups using Pearson’s chi-squared test or Fisher’s exact test as appropriate. RESULTS: Of the 6526 participants, the overall prevalence was 8.27% for schistosomiasis and 2.67% for HBV. The prevalence of hepatitis B among participants who were Schistosoma antibody positive (25.37%) was higher than the prevalence in participants who were Schistosoma antibody negative (0.62%; χ(2)=1169.358, p<0.001, odds ratio 54.659). We also observed that there was no difference in the prevalence of hepatitis B between males and females in areas where schistosomiasis was endemic (χ(2)=1.827, p=0.177), but the prevalence of hepatitis B in middle-aged people was higher than in other age groups (χ(2)=47.877, p<0.001). CONCLUSIONS: There was an association between schistosomiasis and HBV infection. However, more work is needed to find the causal relationship between schistosomiasis and HBV infection.
format Online
Article
Text
id pubmed-7064163
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-70641632020-03-13 Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China Zhang, Yupeng Xie, Yaofei Chen, Qi Chen, Xuyu Dong, Zhuangzhuang Tan, Xiaodong Trans R Soc Trop Med Hyg Original Article BACKGROUND: Both hepatitis B virus (HBV) infection and schistosomiasis are important public health problems in China. Concurrent infection between HBV and schistosomiasis is often observed in areas where schistosomiasis is endemic. The aim of this study was to determine the prevalence of schistosomiasis and HBV in schistosomiasis-affected areas, to explore whether schistosomiasis patients are more susceptible to HBV and to determine if the prevalence of HBV in high-endemic areas of schistosomiasis is higher than in low-endemic areas. METHODS: A total of 6526 participants from 13 villages in Hubei province were included in a cross-sectional study and blood samples were collected and examined. Qualitative variables were compared between groups using Pearson’s chi-squared test or Fisher’s exact test as appropriate. RESULTS: Of the 6526 participants, the overall prevalence was 8.27% for schistosomiasis and 2.67% for HBV. The prevalence of hepatitis B among participants who were Schistosoma antibody positive (25.37%) was higher than the prevalence in participants who were Schistosoma antibody negative (0.62%; χ(2)=1169.358, p<0.001, odds ratio 54.659). We also observed that there was no difference in the prevalence of hepatitis B between males and females in areas where schistosomiasis was endemic (χ(2)=1.827, p=0.177), but the prevalence of hepatitis B in middle-aged people was higher than in other age groups (χ(2)=47.877, p<0.001). CONCLUSIONS: There was an association between schistosomiasis and HBV infection. However, more work is needed to find the causal relationship between schistosomiasis and HBV infection. Oxford University Press 2020-02 2019-11-12 /pmc/articles/PMC7064163/ /pubmed/31722017 http://dx.doi.org/10.1093/trstmh/trz086 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Zhang, Yupeng
Xie, Yaofei
Chen, Qi
Chen, Xuyu
Dong, Zhuangzhuang
Tan, Xiaodong
Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title_full Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title_fullStr Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title_full_unstemmed Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title_short Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
title_sort prevalence and co-infection of schistosomiasis/hepatitis b among rural populations in endemic areas in hubei, china
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064163/
https://www.ncbi.nlm.nih.gov/pubmed/31722017
http://dx.doi.org/10.1093/trstmh/trz086
work_keys_str_mv AT zhangyupeng prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina
AT xieyaofei prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina
AT chenqi prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina
AT chenxuyu prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina
AT dongzhuangzhuang prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina
AT tanxiaodong prevalenceandcoinfectionofschistosomiasishepatitisbamongruralpopulationsinendemicareasinhubeichina