CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40

Inflammatory bowel diseases (IBD) are complex, multifactorial disorders characterized by chronic relapsing intestinal inflammation. IBD is diagnosed around 1 in 1000 individuals in Western countries with globally increasing incident rates. Association studies have identified hundreds of genes that a...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Graham, Sean, Sun, Ning, McCarthy, Donna, Peng, Ruoqi, Erickson, Jamie, Oconnor, Liz, Zhu, Xiaochun, Wurbel, Marc, Dunstan, Robert, Westmoreland, Susan, Chung, Namjin, Ghayur, Tariq, Gu, Jijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064223/
https://www.ncbi.nlm.nih.gov/pubmed/32155151
http://dx.doi.org/10.1371/journal.pone.0228221

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