Cargando…

Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)

BACKGROUND: Perfluorooctanoic acid (PFOA) is a poly- and perfluoroalkyl substance (PFAS) associated with adverse pregnancy outcomes in mice and humans, but little is known regarding one of its replacements, hexafluoropropylene oxide dimer acid (HFPO-DA, referred to here as GenX), both of which have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blake, Bevin E., Cope, Harlie A., Hall, Samantha M., Keys, Robert D., Mahler, Beth W., McCord, James, Scott, Brittany, Stapleton, Heather M., Strynar, Mark J., Elmore, Susan A., Fenton, Suzanne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Environmental Health Perspectives 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064328/ https://www.ncbi.nlm.nih.gov/pubmed/32074459 http://dx.doi.org/10.1289/EHP6233

Ejemplares similares

Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation
por: Cope, Harlie A., et al.
Publicado: (2021)

Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice
por: Blake, Bevin E., et al.
Publicado: (2022)

Adverse Maternal, Fetal, and Postnatal Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) from Oral Gestational Exposure in Sprague-Dawley Rats
por: Conley, Justin M., et al.
Publicado: (2019)

Hexafluoropropylene oxide dimer acid (GenX) exposure induces apoptosis in HepG2 cells
por: Yoo, Hee Joon, et al.
Publicado: (2021)

Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat
por: Conley, Justin M., et al.
Publicado: (2022)

Evaluation of Developmental Toxicity, Developmental Neurotoxicity, and Tissue Dose in Zebrafish Exposed to GenX and Other PFAS
por: Gaballah, Shaza, et al.
Publicado: (2020)

Blood transcriptome responses to PFOA and GenX treatment in the marsupial biomedical model Monodelphis domestica
por: Cao, Wenqi, et al.
Publicado: (2023)

Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)
por: Steenland, Kyle, et al.
Publicado: (2010)

Activated Persulfate Oxidation of Perfluorooctanoic Acid (PFOA) in Groundwater under Acidic Conditions
por: Yin, Penghua, et al.
Publicado: (2016)

Association of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) with Uric Acid among Adults with Elevated Community Exposure to PFOA
por: Steenland, Kyle, et al.
Publicado: (2010)

Complete mineralization of perfluorooctanoic acid (PFOA) by γ-irradiation in aqueous solution
por: Zhang, Ze, et al.
Publicado: (2014)

Accumulation and Clearance of Perfluorooctanoic Acid (PFOA) in Current and Former Residents of an Exposed Community
por: Seals, Ryan, et al.
Publicado: (2011)

Perfluorooctanoic Acid (PFOA) Induces Redox Status Disruption in Swine Granulosa Cells
por: Basini, Giuseppina, et al.
Publicado: (2022)

Detail study on the interaction between perfluorooctanoic acid (PFOA) with human hemoglobin (Hb)
por: Perera, N.L. Dilani, et al.
Publicado: (2023)

Exposure to perfluorooctanoic acid (PFOA) decreases neutrophil migration response to injury in zebrafish embryos
por: Pecquet, Alison M., et al.
Publicado: (2020)

Perfluorooctanoic acid (PFOA) exposure in relation to the kidneys: A review of current available literature
por: Liu, Dongge, et al.
Publicado: (2023)

Computational Analysis of the Binding Mechanism of GenX and HSA
por: Delva-Wiley, Jeannette, et al.
Publicado: (2021)

GenX 3: the latest generation of an established tool
por: Glavic, Artur, et al.
Publicado: (2022)

Serum perfluorooctanoic acid (PFOA) concentrations in normal and hyperlipidemic female hamsters dosed orally with ammonium perfluorooctanoate (APFO) for up to 30 days
por: Everds, Nancy E., et al.
Publicado: (2015)

Modeled Perfluorooctanoic Acid (PFOA) Exposure and Liver Function in a Mid-Ohio Valley Community
por: Darrow, Lyndsey A., et al.
Publicado: (2016)

Toxicity Effects of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) on Two Green Microalgae Species
por: Mojiri, Amin, et al.
Publicado: (2023)

Research Updates on the Mechanism and Influencing Factors of the Photocatalytic Degradation of Perfluorooctanoic Acid (PFOA) in Water Environments
por: Liang, Jie, et al.
Publicado: (2023)

Highly effective removal of perfluorooctanoic acid (PFOA) in water with DBD-plasma-enhanced rice husks
por: Sahara, Thera, et al.
Publicado: (2023)

Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma cells
por: Behr, Anne-Cathrin, et al.
Publicado: (2020)

Development of an oral reference dose for the perfluorinated compound GenX
por: Thompson, Chad M., et al.
Publicado: (2019)

Perfluorooctanoic Acid (PFOA) Exposures and Incident Cancers among Adults Living Near a Chemical Plant
por: Barry, Vaughn, et al.
Publicado: (2013)

Metabolic Profiling of Chicken Embryos Exposed to Perfluorooctanoic Acid (PFOA) and Agonists to Peroxisome Proliferator-Activated Receptors
por: Mattsson, Anna, et al.
Publicado: (2015)

Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells
por: Pierozan, Paula, et al.
Publicado: (2018)

Presence and biodistribution of perfluorooctanoic acid (PFOA) in Paracentrotus lividus highlight its potential application for environmental biomonitoring
por: Savoca, Dario, et al.
Publicado: (2021)

Human Evidence of Perfluorooctanoic Acid (PFOA) Exposure on Hepatic Disease: A Systematic Review and Meta-Analysis
por: Choi, Jihee, et al.
Publicado: (2022)

Association between Serum Perfluorooctanoic Acid (PFOA) and Thyroid Disease in the U.S. National Health and Nutrition Examination Survey
por: Melzer, David, et al.
Publicado: (2010)

Serum Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) Concentrations and Liver Function Biomarkers in a Population with Elevated PFOA Exposure
por: Gallo, Valentina, et al.
Publicado: (2012)

Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)
por: Convertino, Matteo, et al.
Publicado: (2018)

Ulcerative Colitis and Perfluorooctanoic Acid (PFOA) in a Highly Exposed Population of Community Residents and Workers in the Mid-Ohio Valley
por: Steenland, Kyle, et al.
Publicado: (2013)

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro
por: Pierozan, Paula, et al.
Publicado: (2020)

Prenatal Exposure to Perfluorooctanoate (PFOA) and Perfluorooctanesulfonate (PFOS) and Maternally Reported Developmental Milestones in Infancy
por: Fei, Chunyuan, et al.
Publicado: (2008)

Private Drinking Water Wells as a Source of Exposure to Perfluorooctanoic Acid (PFOA) in Communities Surrounding a Fluoropolymer Production Facility
por: Hoffman, Kate, et al.
Publicado: (2011)

Perfluorooctanoic Acid (PFOA) Exposure in Early Life Increases Risk of Childhood Adiposity: A Meta-Analysis of Prospective Cohort Studies
por: Liu, Pingping, et al.
Publicado: (2018)

Perfluorooctanoic Acid (PFOA) Exposure and Abnormal Alanine Aminotransferase: Using Clinical Consensus Cutoffs Compared to Statistical Cutoffs for Abnormal Values
por: Ducatman, Alan, et al.
Publicado: (2023)

Reusable Functionalized Hydrogel Sorbents for Removing Long- and Short-Chain Perfluoroalkyl Acids (PFAAs) and GenX from Aqueous Solution
por: Huang, Po-Jung, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vosoo9g2tk4r1b0rcc09934vqu