Structural model for differential cap maturation at growing microtubule ends

Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural changes in the lattice, which are responsible for interaction with regulatory f...

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Detalles Bibliográficos
Autores principales: Estévez-Gallego, Juan, Josa-Prado, Fernando, Ku, Siou, Buey, Ruben M, Balaguer, Francisco A, Prota, Andrea E, Lucena-Agell, Daniel, Kamma-Lorger, Christina, Yagi, Toshiki, Iwamoto, Hiroyuki, Duchesne, Laurence, Barasoain, Isabel, Steinmetz, Michel O, Chrétien, Denis, Kamimura, Shinji, Díaz, J Fernando, Oliva, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064335/
https://www.ncbi.nlm.nih.gov/pubmed/32151315
http://dx.doi.org/10.7554/eLife.50155

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