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The detection of age groups by dynamic gait outcomes using machine learning approaches

Prevalence of gait impairments increases with age and is associated with mobility decline, fall risk and loss of independence. For geriatric patients, the risk of having gait disorders is even higher. Consequently, gait assessment in the clinics has become increasingly important. The purpose of the...

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Autores principales: Zhou, Yuhan, Romijnders, Robbin, Hansen, Clint, Campen, Jos van, Maetzler, Walter, Hortobágyi, Tibor, Lamoth, Claudine J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064519/
https://www.ncbi.nlm.nih.gov/pubmed/32157168
http://dx.doi.org/10.1038/s41598-020-61423-2
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author Zhou, Yuhan
Romijnders, Robbin
Hansen, Clint
Campen, Jos van
Maetzler, Walter
Hortobágyi, Tibor
Lamoth, Claudine J. C.
author_facet Zhou, Yuhan
Romijnders, Robbin
Hansen, Clint
Campen, Jos van
Maetzler, Walter
Hortobágyi, Tibor
Lamoth, Claudine J. C.
author_sort Zhou, Yuhan
collection PubMed
description Prevalence of gait impairments increases with age and is associated with mobility decline, fall risk and loss of independence. For geriatric patients, the risk of having gait disorders is even higher. Consequently, gait assessment in the clinics has become increasingly important. The purpose of the present study was to classify healthy young-middle aged, older adults and geriatric patients based on dynamic gait outcomes. Classification performance of three supervised machine learning methods was compared. From trunk 3D-accelerations of 239 subjects obtained during walking, 23 dynamic gait outcomes were calculated. Kernel Principal Component Analysis (KPCA) was applied for dimensionality reduction of the data for Support Vector Machine (SVM) classification. Random Forest (RF) and Artificial Neural Network (ANN) were applied to the 23 gait outcomes without prior data reduction. Classification accuracy of SVM was 89%, RF accuracy was 73%, and ANN accuracy was 90%. Gait outcomes that significantly contributed to classification included: Root Mean Square (Anterior-Posterior, Vertical), Cross Entropy (Medio-Lateral, Vertical), Lyapunov Exponent (Vertical), step regularity (Vertical) and gait speed. ANN is preferable due to the automated data reduction and significant gait outcome identification. For clinicians, these gait outcomes could be used for diagnosing subjects with mobility disabilities, fall risk and to monitor interventions.
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spelling pubmed-70645192020-03-18 The detection of age groups by dynamic gait outcomes using machine learning approaches Zhou, Yuhan Romijnders, Robbin Hansen, Clint Campen, Jos van Maetzler, Walter Hortobágyi, Tibor Lamoth, Claudine J. C. Sci Rep Article Prevalence of gait impairments increases with age and is associated with mobility decline, fall risk and loss of independence. For geriatric patients, the risk of having gait disorders is even higher. Consequently, gait assessment in the clinics has become increasingly important. The purpose of the present study was to classify healthy young-middle aged, older adults and geriatric patients based on dynamic gait outcomes. Classification performance of three supervised machine learning methods was compared. From trunk 3D-accelerations of 239 subjects obtained during walking, 23 dynamic gait outcomes were calculated. Kernel Principal Component Analysis (KPCA) was applied for dimensionality reduction of the data for Support Vector Machine (SVM) classification. Random Forest (RF) and Artificial Neural Network (ANN) were applied to the 23 gait outcomes without prior data reduction. Classification accuracy of SVM was 89%, RF accuracy was 73%, and ANN accuracy was 90%. Gait outcomes that significantly contributed to classification included: Root Mean Square (Anterior-Posterior, Vertical), Cross Entropy (Medio-Lateral, Vertical), Lyapunov Exponent (Vertical), step regularity (Vertical) and gait speed. ANN is preferable due to the automated data reduction and significant gait outcome identification. For clinicians, these gait outcomes could be used for diagnosing subjects with mobility disabilities, fall risk and to monitor interventions. Nature Publishing Group UK 2020-03-10 /pmc/articles/PMC7064519/ /pubmed/32157168 http://dx.doi.org/10.1038/s41598-020-61423-2 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zhou, Yuhan
Romijnders, Robbin
Hansen, Clint
Campen, Jos van
Maetzler, Walter
Hortobágyi, Tibor
Lamoth, Claudine J. C.
The detection of age groups by dynamic gait outcomes using machine learning approaches
title The detection of age groups by dynamic gait outcomes using machine learning approaches
title_full The detection of age groups by dynamic gait outcomes using machine learning approaches
title_fullStr The detection of age groups by dynamic gait outcomes using machine learning approaches
title_full_unstemmed The detection of age groups by dynamic gait outcomes using machine learning approaches
title_short The detection of age groups by dynamic gait outcomes using machine learning approaches
title_sort detection of age groups by dynamic gait outcomes using machine learning approaches
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064519/
https://www.ncbi.nlm.nih.gov/pubmed/32157168
http://dx.doi.org/10.1038/s41598-020-61423-2
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