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MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma
There is a lack of well validated prognostic biomarkers in osteosarcoma, a rare, recalcitrant disease for which treatment standards have not changed in over 20 years. We performed microRNA sequencing in 74 frozen osteosarcoma biopsy samples, constituting the largest single center translationally ana...
Autores principales: | Lietz, Christopher E., Garbutt, Cassandra, Barry, William T., Deshpande, Vikram, Chen, Yen-Lin, Lozano-Calderon, Santiago A., Wang, Yaoyu, Lawney, Brian, Ebb, David, Cote, Gregory M., Duan, Zhenfeng, Hornicek, Francis J., Choy, Edwin, Petur Nielsen, G., Haibe-Kains, Benjamin, Quackenbush, John, Spentzos, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064533/ https://www.ncbi.nlm.nih.gov/pubmed/32157112 http://dx.doi.org/10.1038/s41598-020-61236-3 |
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