Cancer associated fibroblast FAK regulates malignant cell metabolism

Emerging evidence suggests that cancer cell metabolism can be regulated by cancer-associated fibroblasts (CAFs), but the mechanisms are poorly defined. Here we show that CAFs regulate malignant cell metabolism through pathways under the control of FAK. In breast and pancreatic cancer patients we fin...

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Detalles Bibliográficos
Autores principales: Demircioglu, Fevzi, Wang, Jun, Candido, Juliana, Costa, Ana S. H., Casado, Pedro, de Luxan Delgado, Beatriz, Reynolds, Louise E., Gomez-Escudero, Jesus, Newport, Emma, Rajeeve, Vinothini, Baker, Ann-Marie, Roy-Luzarraga, Marina, Graham, Trevor A., Foster, Julie, Wang, Yu, Campbell, James J., Singh, Rajinder, Zhang, Penglie, Schall, Thomas J., Balkwill, Frances R., Sosabowski, Jane, Cutillas, Pedro R., Frezza, Christian, Sancho, Patricia, Hodivala-Dilke, Kairbaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064590/
https://www.ncbi.nlm.nih.gov/pubmed/32157087
http://dx.doi.org/10.1038/s41467-020-15104-3

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