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Characteristics of Tumor-Infiltrating Lymphocytes Prior to and During Immune Checkpoint Inhibitor Therapy
The tumor immune contexture plays a major role for the clinical outcome of patients. High densities of CD45RO(+) T helper 1 cells and CD8(+) T cells are associated with improved survival of patients with various cancer entities. In contrast, a higher frequency of tumor-infiltrating M2 macrophages is...
Autores principales: | Plesca, Ioana, Tunger, Antje, Müller, Luise, Wehner, Rebekka, Lai, Xixi, Grimm, Marc-Oliver, Rutella, Sergio, Bachmann, Michael, Schmitz, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064638/ https://www.ncbi.nlm.nih.gov/pubmed/32194568 http://dx.doi.org/10.3389/fimmu.2020.00364 |
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