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Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response
Although the pathogen recognition receptor pathways that activate cell-intrinsic antiviral responses are well delineated, less is known about how the host regulates this response to prevent sustained signaling and possible immune-mediated damage. Using a genome-wide CRISPR-Cas9 screening approach to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064753/ https://www.ncbi.nlm.nih.gov/pubmed/32156810 http://dx.doi.org/10.1128/mBio.00136-20 |