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Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response

Although the pathogen recognition receptor pathways that activate cell-intrinsic antiviral responses are well delineated, less is known about how the host regulates this response to prevent sustained signaling and possible immune-mediated damage. Using a genome-wide CRISPR-Cas9 screening approach to...

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Detalles Bibliográficos
Autores principales: Ma, Hongming, Qian, Wei, Bambouskova, Monika, Collins, Patrick L., Porter, Sofia I., Byrum, Andrea K., Zhang, Rong, Artyomov, Maxim, Oltz, Eugene M., Mosammaparast, Nima, Miner, Jonathan J., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064753/
https://www.ncbi.nlm.nih.gov/pubmed/32156810
http://dx.doi.org/10.1128/mBio.00136-20

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