Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae

Transporters belonging to the chromosomally encoded resistance-nodulation-division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the cotransfer of large gene clusters encoding RND-type pumps from the chromosome to a plasmid appears infrequent, and no plasmid-medi...

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Detalles Bibliográficos
Autores principales: Lv, Luchao, Wan, Miao, Wang, Chengzhen, Gao, Xun, Yang, Qiwen, Partridge, Sally R., Wang, Yang, Zong, Zhiyong, Doi, Yohei, Shen, Jianzhong, Jia, Peiyao, Song, Qianhua, Zhang, Qianhui, Yang, Jun, Huang, Xianhui, Wang, Minggui, Liu, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064769/
https://www.ncbi.nlm.nih.gov/pubmed/32127452
http://dx.doi.org/10.1128/mBio.02930-19

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