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The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing
The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly binds to...
Autores principales: | Thuenauer, Roland, Landi, Alessia, Trefzer, Anne, Altmann, Silke, Wehrum, Sarah, Eierhoff, Thorsten, Diedrich, Britta, Dengjel, Jörn, Nyström, Alexander, Imberty, Anne, Römer, Winfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064779/ https://www.ncbi.nlm.nih.gov/pubmed/32156827 http://dx.doi.org/10.1128/mBio.03260-19 |
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