Cargando…

Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature

Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metas...

Descripción completa

Detalles Bibliográficos
Autores principales: Makar, Gabriel S., Makar, Michael, Ghobrial, Joanna, Bush, Kathryn, Gruner, Ryan Allen, Holdbrook, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064852/
https://www.ncbi.nlm.nih.gov/pubmed/32181035
http://dx.doi.org/10.1155/2020/1989452
_version_ 1783504945702502400
author Makar, Gabriel S.
Makar, Michael
Ghobrial, Joanna
Bush, Kathryn
Gruner, Ryan Allen
Holdbrook, Thomas
author_facet Makar, Gabriel S.
Makar, Michael
Ghobrial, Joanna
Bush, Kathryn
Gruner, Ryan Allen
Holdbrook, Thomas
author_sort Makar, Gabriel S.
collection PubMed
description Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females.
format Online
Article
Text
id pubmed-7064852
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-70648522020-03-16 Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature Makar, Gabriel S. Makar, Michael Ghobrial, Joanna Bush, Kathryn Gruner, Ryan Allen Holdbrook, Thomas Case Rep Oncol Med Case Report Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females. Hindawi 2020-02-28 /pmc/articles/PMC7064852/ /pubmed/32181035 http://dx.doi.org/10.1155/2020/1989452 Text en Copyright © 2020 Gabriel S. Makar et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Makar, Gabriel S.
Makar, Michael
Ghobrial, Joanna
Bush, Kathryn
Gruner, Ryan Allen
Holdbrook, Thomas
Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title_full Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title_fullStr Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title_full_unstemmed Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title_short Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature
title_sort malignant phyllodes tumor in an adolescent female: a rare case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064852/
https://www.ncbi.nlm.nih.gov/pubmed/32181035
http://dx.doi.org/10.1155/2020/1989452
work_keys_str_mv AT makargabriels malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature
AT makarmichael malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature
AT ghobrialjoanna malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature
AT bushkathryn malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature
AT grunerryanallen malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature
AT holdbrookthomas malignantphyllodestumorinanadolescentfemaleararecasereportandreviewoftheliterature