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Repurposing the Pummerer Rearrangement: Determination of Methionine Sulfoxides in Peptides

The reversible oxidation of methionine residues in proteins has emerged as a biologically important post‐translational modification. However, detection and quantitation of methionine sulfoxide in proteins is difficult. Our aim is to develop a method for specifically derivatizing methionine sulfoxide...

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Detalles Bibliográficos
Autores principales: Woodroofe, Carolyn C., Ivanic, Joseph, Monti, Sarah, Levine, Rodney L., Swenson, Rolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065062/
https://www.ncbi.nlm.nih.gov/pubmed/31365170
http://dx.doi.org/10.1002/cbic.201900463

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