Cargando…

Tumour‐cell‐derived complement components C1r and C1s promote growth of cutaneous squamous cell carcinoma

BACKGROUND: The incidence of epidermal keratinocyte‐derived cutaneous squamous cell carcinoma (cSCC) is increasing worldwide. OBJECTIVES: To study the role of the complement classical pathway components C1q, C1r and C1s in the progression of cSCC. METHODS: The mRNA levels of C1Q subunits and C1R and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riihilä, P., Viiklepp, K., Nissinen, L., Farshchian, M., Kallajoki, M., Kivisaari, A., Meri, S., Peltonen, J., Peltonen, S., Kähäri, V.‐M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065064/ https://www.ncbi.nlm.nih.gov/pubmed/31049937 http://dx.doi.org/10.1111/bjd.18095

Ejemplares similares

Complement Factor D Is a Novel Biomarker and Putative Therapeutic Target in Cutaneous Squamous Cell Carcinoma
por: Rahmati Nezhad, Pegah, et al.
Publicado: (2022)

Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma
por: Farshchian, Mehdi, et al.
Publicado: (2017)

Complement System in Cutaneous Squamous Cell Carcinoma
por: Riihilä, Pilvi, et al.
Publicado: (2019)

Super Enhancer-Regulated LINC00094 (SERLOC) Upregulates the Expression of MMP-1 and MMP-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma
por: Piipponen, Minna, et al.
Publicado: (2022)

Inhibition of TGF-β signaling, invasion, and growth of cutaneous squamous cell carcinoma by PLX8394
por: Siljamäki, Elina, et al.
Publicado: (2023)

The Role of p53 in Progression of Cutaneous Squamous Cell Carcinoma
por: Piipponen, Minna, et al.
Publicado: (2021)

Risk Factors and Prognosis for Metastatic Cutaneous Squamous Cell Carcinoma: A Cohort Study
por: KNUUTILA, Jaakko S., et al.
Publicado: (2020)

Identification of metastatic primary cutaneous squamous cell carcinoma utilizing artificial intelligence analysis of whole slide images
por: Knuutila, Jaakko S., et al.
Publicado: (2022)

Signaling pathways in human osteoclasts differentiation: ERK1/2 as a key player
por: Pennanen, Paula, et al.
Publicado: (2021)

Keratinocyte Growth Factor Induces Gene Expression Signature Associated with Suppression of Malignant Phenotype of Cutaneous Squamous Carcinoma Cells
por: Toriseva, Mervi, et al.
Publicado: (2012)

Matrix metalloproteinases in keratinocyte carcinomas
por: Riihilä, Pilvi, et al.
Publicado: (2020)

Tumor cell-specific Serpin A1 expression in vulvar squamous cell carcinoma
por: Lagerstedt, Maria, et al.
Publicado: (2019)

Long non-coding RNAs in cutaneous biology and keratinocyte carcinomas
por: Piipponen, Minna, et al.
Publicado: (2020)

Retrospective, Registry-based, Cohort Investigation of Clinical Outcomes in Patients with Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma in Finland
por: TUOMINEN, Samuli, et al.
Publicado: (2022)

Long non-coding RNA PICSAR decreases adhesion and promotes migration of squamous carcinoma cells by downregulating α2β1 and α5β1 integrin expression
por: Piipponen, Minna, et al.
Publicado: (2018)

The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis
por: Sikora, Justyna, et al.
Publicado: (2018)

Unusual Case of Inflammatory Myofibroblastic Tumor in Maxilla
por: Rautava, Jaana, et al.
Publicado: (2013)

Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone
por: Alpay, Kemal, et al.
Publicado: (2014)

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis
por: Lubbers, Rosalie, et al.
Publicado: (2018)

Complement C3a promotes proliferation, migration and stemness in cutaneous squamous cell carcinoma
por: Fan, Zhuo, et al.
Publicado: (2019)

THE FIXATION OF COMPLEMENT AND THE ACTIVATED FIRST COMPONENT (C1) OF COMPLEMENT BY COMPLEXES FORMED BETWEEN ANTIBODY AND DIVALENT HAPTEN
por: Hyslop, N. E., et al.
Publicado: (1970)

Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma
por: Yang, Huanglong, et al.
Publicado: (2022)

Autoantibodies against Complement Classical Pathway Components C1q, C1r, C1s and C1-Inh in Patients with Lupus Nephritis
por: Radanova, Maria, et al.
Publicado: (2022)

Secretion of soluble complement inhibitors factor H and factor H-like protein (FHL-1) by ovarian tumour cells
por: Junnikkala, S, et al.
Publicado: (2002)

C'1 ESTERASE EFFECT ON ACTIVITY AND PHYSICOCHEMICAL PROPERTIES OF THE FOURTH COMPONENT OF COMPLEMENT
por: Müller-Eberhard, Hans J., et al.
Publicado: (1965)

Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
por: Avirutnan, Panisadee, et al.
Publicado: (2010)

MafB is a critical regulator of complement component C1q
por: Tran, Mai Thi Nhu, et al.
Publicado: (2017)

Autoantibodies against complement component C1q in systemic lupus erythematosus
por: Trendelenburg, Marten
Publicado: (2021)

Structure of the C1r–C1s interaction of the C1 complex of complement activation
por: Almitairi, Jamal O. M., et al.
Publicado: (2018)

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
por: Khoa, D. V. A., et al.
Publicado: (2015)

Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis
por: Xu, Bei, et al.
Publicado: (2019)

Complement Component C1q as an Emerging Biomarker for the Diagnosis of Tuberculous Pleural Effusion
por: Qiao, Xin, et al.
Publicado: (2021)

THE SECOND COMPONENT OF HUMAN COMPLEMENT: ITS ISOLATION, FRAGMENTATION BY C'1 ESTERASE, AND INCORPORATION INTO C'3 CONVERTASE
por: Polley, Margaret J., et al.
Publicado: (1968)

Quantitative Visualization of the Interaction between Complement Component C1 and Immunoglobulin G: The Effect of C(H)1 Domain Deletion
por: Yanaka, Saeko, et al.
Publicado: (2022)

Components of the Lectin Pathway of Complement in Solid Tumour Cancers
por: Cedzyński, Maciej, et al.
Publicado: (2022)

Craniofacial and oral alterations in patients with Neurofibromatosis 1
por: Visnapuu, Vivian, et al.
Publicado: (2018)

Anti-C1q antibodies and their association with complement components in Indian systemic lupus erythematosus patients
por: Pradhan, V., et al.
Publicado: (2012)

Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis
por: Malminen, Maria, et al.
Publicado: (2002)

Complement Component C1q: Historical Perspective of a Functionally Versatile, and Structurally Unusual, Serum Protein
por: Reid, Kenneth B. M.
Publicado: (2018)

Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells
por: Freda, Christopher T., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_267ksuocck8sl39n8hnqi04g5o