The mycolic acid reductase Rv2509 has distinct structural motifs and is essential for growth in slow‐growing mycobacteria

The final step in mycolic acid biosynthesis in Mycobacterium tuberculosis is catalysed by mycolyl reductase encoded by the Rv2509 gene. Sequence analysis and homology modelling indicate that Rv2509 belongs to the short‐chain fatty acid dehydrogenase/reductase (SDR) family, but with some distinct fea...

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Detalles Bibliográficos
Autores principales: Javid, Asma, Cooper, Charlotte, Singh, Albel, Schindler, Steffen, Hänisch, Milena, Marshall, Robert L., Kalscheuer, Rainer, Bavro, Vassiliy N., Bhatt, Apoorva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065075/
https://www.ncbi.nlm.nih.gov/pubmed/31785114
http://dx.doi.org/10.1111/mmi.14437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065075/
https://www.ncbi.nlm.nih.gov/pubmed/31785114
http://dx.doi.org/10.1111/mmi.14437

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