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Adaptive multiarm multistage clinical trials

Two methods for designing adaptive multiarm multistage (MAMS) clinical trials, originating from conceptually different group sequential frameworks are presented, and their operating characteristics are compared. In both methods pairwise comparisons are made, stage‐by‐stage, between each treatment ar...

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Detalles Bibliográficos
Autores principales: Ghosh, Pranab, Liu, Lingyun, Mehta, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065228/
https://www.ncbi.nlm.nih.gov/pubmed/32048313
http://dx.doi.org/10.1002/sim.8464