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Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway
Dimethyl itaconate (DI) is a membrane‐permeable itaconate derivative with anti‐inflammatory functions. However, the anti‐inflammatory effect of DI has never been studied in fungal keratitis. In this study, we tested the protective effect of DI against fungal keratitis and assessed the role of NF‐E2‐...
Autores principales: | Gu, Lingwen, Lin, Jing, Wang, Qian, Li, Cui, Peng, Xudong, Fan, Yiqun, Lu, Chunli, Lin, Hao, Niu, Yawen, Zhu, Guoqiang, Zhao, Guiqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065235/ https://www.ncbi.nlm.nih.gov/pubmed/31943336 http://dx.doi.org/10.1111/imcb.12316 |
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