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Shrimp sensitization in house dust mite allergic patients

Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In to...

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Autores principales: Ukleja-Sokołowska, Natalia, Gawrońska-Ukleja, Ewa, Lis, Kinga, Żbikowska-Gotz, Magdalena, Adamczak, Rafał, Sokołowski, Łukasz, Bartuzi, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065430/
https://www.ncbi.nlm.nih.gov/pubmed/32138565
http://dx.doi.org/10.1177/2058738420907188
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author Ukleja-Sokołowska, Natalia
Gawrońska-Ukleja, Ewa
Lis, Kinga
Żbikowska-Gotz, Magdalena
Adamczak, Rafał
Sokołowski, Łukasz
Bartuzi, Zbigniew
author_facet Ukleja-Sokołowska, Natalia
Gawrońska-Ukleja, Ewa
Lis, Kinga
Żbikowska-Gotz, Magdalena
Adamczak, Rafał
Sokołowski, Łukasz
Bartuzi, Zbigniew
author_sort Ukleja-Sokołowska, Natalia
collection PubMed
description Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable.
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spelling pubmed-70654302020-03-25 Shrimp sensitization in house dust mite allergic patients Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew Int J Immunopathol Pharmacol Original Research Article Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable. SAGE Publications 2020-03-05 /pmc/articles/PMC7065430/ /pubmed/32138565 http://dx.doi.org/10.1177/2058738420907188 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Ukleja-Sokołowska, Natalia
Gawrońska-Ukleja, Ewa
Lis, Kinga
Żbikowska-Gotz, Magdalena
Adamczak, Rafał
Sokołowski, Łukasz
Bartuzi, Zbigniew
Shrimp sensitization in house dust mite allergic patients
title Shrimp sensitization in house dust mite allergic patients
title_full Shrimp sensitization in house dust mite allergic patients
title_fullStr Shrimp sensitization in house dust mite allergic patients
title_full_unstemmed Shrimp sensitization in house dust mite allergic patients
title_short Shrimp sensitization in house dust mite allergic patients
title_sort shrimp sensitization in house dust mite allergic patients
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065430/
https://www.ncbi.nlm.nih.gov/pubmed/32138565
http://dx.doi.org/10.1177/2058738420907188
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