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Shrimp sensitization in house dust mite allergic patients
Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065430/ https://www.ncbi.nlm.nih.gov/pubmed/32138565 http://dx.doi.org/10.1177/2058738420907188 |
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author | Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew |
author_facet | Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew |
author_sort | Ukleja-Sokołowska, Natalia |
collection | PubMed |
description | Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable. |
format | Online Article Text |
id | pubmed-7065430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-70654302020-03-25 Shrimp sensitization in house dust mite allergic patients Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew Int J Immunopathol Pharmacol Original Research Article Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable. SAGE Publications 2020-03-05 /pmc/articles/PMC7065430/ /pubmed/32138565 http://dx.doi.org/10.1177/2058738420907188 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Article Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew Shrimp sensitization in house dust mite allergic patients |
title | Shrimp sensitization in house dust mite allergic
patients |
title_full | Shrimp sensitization in house dust mite allergic
patients |
title_fullStr | Shrimp sensitization in house dust mite allergic
patients |
title_full_unstemmed | Shrimp sensitization in house dust mite allergic
patients |
title_short | Shrimp sensitization in house dust mite allergic
patients |
title_sort | shrimp sensitization in house dust mite allergic
patients |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065430/ https://www.ncbi.nlm.nih.gov/pubmed/32138565 http://dx.doi.org/10.1177/2058738420907188 |
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