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Original and generic preservation solutions in organ transplantation. A new paradigm?

Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The rece...

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Autores principales: Roselló-Catafau, Joan, Panisello-Roselló, Arnau, Pasut, Gianfranco, Navasa, Miquel, Pirenne, Jacques, Adam, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065442/
https://www.ncbi.nlm.nih.gov/pubmed/32159587
http://dx.doi.org/10.1590/s0102-865020200010000001
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author Roselló-Catafau, Joan
Panisello-Roselló, Arnau
Pasut, Gianfranco
Navasa, Miquel
Pirenne, Jacques
Adam, René
author_facet Roselló-Catafau, Joan
Panisello-Roselló, Arnau
Pasut, Gianfranco
Navasa, Miquel
Pirenne, Jacques
Adam, René
author_sort Roselló-Catafau, Joan
collection PubMed
description Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation solutions (solutions with the same composition and under the same legislation as the original versions, but with different brands) compelled us to study whether the standards are maintained when comparing the original and its generic counterpart. Along these lines, we discuss and comment on some aspects concerning this issue of general interest in the organ transplantation field.
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spelling pubmed-70654422020-03-19 Original and generic preservation solutions in organ transplantation. A new paradigm? Roselló-Catafau, Joan Panisello-Roselló, Arnau Pasut, Gianfranco Navasa, Miquel Pirenne, Jacques Adam, René Acta Cir Bras Special Article Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation solutions (solutions with the same composition and under the same legislation as the original versions, but with different brands) compelled us to study whether the standards are maintained when comparing the original and its generic counterpart. Along these lines, we discuss and comment on some aspects concerning this issue of general interest in the organ transplantation field. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020-03-09 /pmc/articles/PMC7065442/ /pubmed/32159587 http://dx.doi.org/10.1590/s0102-865020200010000001 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Article
Roselló-Catafau, Joan
Panisello-Roselló, Arnau
Pasut, Gianfranco
Navasa, Miquel
Pirenne, Jacques
Adam, René
Original and generic preservation solutions in organ transplantation. A new paradigm?
title Original and generic preservation solutions in organ transplantation. A new paradigm?
title_full Original and generic preservation solutions in organ transplantation. A new paradigm?
title_fullStr Original and generic preservation solutions in organ transplantation. A new paradigm?
title_full_unstemmed Original and generic preservation solutions in organ transplantation. A new paradigm?
title_short Original and generic preservation solutions in organ transplantation. A new paradigm?
title_sort original and generic preservation solutions in organ transplantation. a new paradigm?
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065442/
https://www.ncbi.nlm.nih.gov/pubmed/32159587
http://dx.doi.org/10.1590/s0102-865020200010000001
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