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Original and generic preservation solutions in organ transplantation. A new paradigm?
Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The rece...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065442/ https://www.ncbi.nlm.nih.gov/pubmed/32159587 http://dx.doi.org/10.1590/s0102-865020200010000001 |
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author | Roselló-Catafau, Joan Panisello-Roselló, Arnau Pasut, Gianfranco Navasa, Miquel Pirenne, Jacques Adam, René |
author_facet | Roselló-Catafau, Joan Panisello-Roselló, Arnau Pasut, Gianfranco Navasa, Miquel Pirenne, Jacques Adam, René |
author_sort | Roselló-Catafau, Joan |
collection | PubMed |
description | Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation solutions (solutions with the same composition and under the same legislation as the original versions, but with different brands) compelled us to study whether the standards are maintained when comparing the original and its generic counterpart. Along these lines, we discuss and comment on some aspects concerning this issue of general interest in the organ transplantation field. |
format | Online Article Text |
id | pubmed-7065442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
record_format | MEDLINE/PubMed |
spelling | pubmed-70654422020-03-19 Original and generic preservation solutions in organ transplantation. A new paradigm? Roselló-Catafau, Joan Panisello-Roselló, Arnau Pasut, Gianfranco Navasa, Miquel Pirenne, Jacques Adam, René Acta Cir Bras Special Article Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage. The condition in which the organ is transplanted is critical for the outcome of the organ recipient. The recent emergence of generic versions of organ preservation solutions (solutions with the same composition and under the same legislation as the original versions, but with different brands) compelled us to study whether the standards are maintained when comparing the original and its generic counterpart. Along these lines, we discuss and comment on some aspects concerning this issue of general interest in the organ transplantation field. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020-03-09 /pmc/articles/PMC7065442/ /pubmed/32159587 http://dx.doi.org/10.1590/s0102-865020200010000001 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Article Roselló-Catafau, Joan Panisello-Roselló, Arnau Pasut, Gianfranco Navasa, Miquel Pirenne, Jacques Adam, René Original and generic preservation solutions in organ transplantation. A new paradigm? |
title | Original and generic preservation solutions in organ transplantation. A new paradigm?
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title_full | Original and generic preservation solutions in organ transplantation. A new paradigm?
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title_fullStr | Original and generic preservation solutions in organ transplantation. A new paradigm?
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title_full_unstemmed | Original and generic preservation solutions in organ transplantation. A new paradigm?
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title_short | Original and generic preservation solutions in organ transplantation. A new paradigm?
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title_sort | original and generic preservation solutions in organ transplantation. a new paradigm? |
topic | Special Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065442/ https://www.ncbi.nlm.nih.gov/pubmed/32159587 http://dx.doi.org/10.1590/s0102-865020200010000001 |
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