Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia

Recalcitrant neonatal hypoglycemia poses a treatment challenge for clinicians. When a patient’s hypoglycemia does not respond to dextrose infusion, several medication options are available, including diazoxide(1,2). Several side effects of diazoxide are described in the literature, including fluid r...

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Detalles Bibliográficos
Autores principales: Theodorou, Christina M., Hirose, Shinjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065533/
https://www.ncbi.nlm.nih.gov/pubmed/32161713
http://dx.doi.org/10.1016/j.epsc.2019.101356
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author Theodorou, Christina M.
Hirose, Shinjiro
author_facet Theodorou, Christina M.
Hirose, Shinjiro
author_sort Theodorou, Christina M.
collection PubMed
description Recalcitrant neonatal hypoglycemia poses a treatment challenge for clinicians. When a patient’s hypoglycemia does not respond to dextrose infusion, several medication options are available, including diazoxide(1,2). Several side effects of diazoxide are described in the literature, including fluid retention with the risk of development of congestive heart failure(3,4). We describe a case of necrotizing enterocolitis in a patient with Beckwith-Wiedemann Syndrome with persistent neonatal hypoglycemia who was treated with increasing doses of diazoxide.
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spelling pubmed-70655332020-03-11 Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia Theodorou, Christina M. Hirose, Shinjiro J Pediatr Surg Case Rep Article Recalcitrant neonatal hypoglycemia poses a treatment challenge for clinicians. When a patient’s hypoglycemia does not respond to dextrose infusion, several medication options are available, including diazoxide(1,2). Several side effects of diazoxide are described in the literature, including fluid retention with the risk of development of congestive heart failure(3,4). We describe a case of necrotizing enterocolitis in a patient with Beckwith-Wiedemann Syndrome with persistent neonatal hypoglycemia who was treated with increasing doses of diazoxide. 2019-11-21 2020-01 /pmc/articles/PMC7065533/ /pubmed/32161713 http://dx.doi.org/10.1016/j.epsc.2019.101356 Text en This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Theodorou, Christina M.
Hirose, Shinjiro
Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title_full Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title_fullStr Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title_full_unstemmed Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title_short Necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
title_sort necrotizing enterocolitis following diazoxide therapy for persistent neonatal hypoglycemia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065533/
https://www.ncbi.nlm.nih.gov/pubmed/32161713
http://dx.doi.org/10.1016/j.epsc.2019.101356
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