Cargando…

Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

Dendritic cells (DCs) are specialized antigen presenting cells that instruct T cell responses through sensing environmental and inflammatory danger signals. Maintaining the homeostasis of the multiple functionally distinct conventional dendritic cells (cDC) subsets that exist in vivo is crucial for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Purvis, Harriet A., Clarke, Fiona, Montgomery, Anna B., Colas, Chloe, Bibby, Jack A., Cornish, Georgina H., Dai, Xuezhi, Dudziak, Diana, Rawlings, David J., Zamoyska, Rose, Guermonprez, Pierre, Cope, Andrew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065600/ https://www.ncbi.nlm.nih.gov/pubmed/32194571 http://dx.doi.org/10.3389/fimmu.2020.00376

Ejemplares similares

Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells
por: Clarke, Fiona, et al.
Publicado: (2017)

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens
por: Clarke, Fiona, et al.
Publicado: (2018)

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses
por: Sanchez-Blanco, Cristina, et al.
Publicado: (2018)

Protein tyrosine phosphatase PTPN22 regulates IL‐1β dependent Th17 responses by modulating dectin‐1 signaling in mice
por: Purvis, Harriet A, et al.
Publicado: (2017)

Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis
por: Salmond, Robert J, et al.
Publicado: (2015)

The tyrosine phosphatase Ptpn22 discriminates weak, self-peptide from strong agonist T cell receptor signals
por: Salmond, Robert J., et al.
Publicado: (2014)

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
por: Sood, Shatakshi, et al.
Publicado: (2016)

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
por: Spalinger, Marianne R., et al.
Publicado: (2023)

PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion
por: Knipper, Johanna A., et al.
Publicado: (2020)

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells
por: Klebanoff, Christopher A., et al.
Publicado: (2013)

ILC3s control splenic cDC homeostasis via lymphotoxin signaling
por: Vanderkerken, Matthias, et al.
Publicado: (2021)

Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer
por: Mcheik, Soha, et al.
Publicado: (2020)

Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors
por: Brownlie, Rebecca J., et al.
Publicado: (2019)

Augmenting E Protein Activity Impairs cDC2 Differentiation at the Pre-cDC Stage
por: Bajana, Sandra, et al.
Publicado: (2020)

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains
por: Caillet-Saguy, Célia, et al.
Publicado: (2017)

PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation
por: Vermeren, Sonja, et al.
Publicado: (2016)

Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis
por: Liu, Xia, et al.
Publicado: (2011)

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity
por: Michaloglou, Chrysiis, et al.
Publicado: (2013)

PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner
por: Spalinger, Marianne R., et al.
Publicado: (2017)

Lung cDC1 and cDC2 dendritic cells priming naive CD8(+) T cells in situ prior to migration to draining lymph nodes
por: Si, Youhui, et al.
Publicado: (2023)

The FERM and PDZ Domain-Containing Protein Tyrosine Phosphatases, PTPN4 and PTPN3, Are Both Dispensable for T Cell Receptor Signal Transduction
por: Bauler, Timothy J., et al.
Publicado: (2008)

cDC1-derived IL-27 regulates small intestinal CD4(+) T cell homeostasis in mice
por: Ahmadi, Fatemeh, et al.
Publicado: (2022)

Beyond cDC1: Emerging Roles of DC Crosstalk in Cancer Immunity
por: Noubade, Rajkumar, et al.
Publicado: (2019)

Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2
por: Bray, Cara, et al.
Publicado: (2018)

Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
por: Cubas, Rafael, et al.
Publicado: (2020)

Characterization and expression of DEC205 in the cDC1 and cDC2 subsets of porcine dendritic cells from spleen, tonsil, and submaxillary and mesenteric lymph nodes
por: Parra-Sánchez, Héctor, et al.
Publicado: (2018)

Harnessing the cDC1-NK Cross-Talk in the Tumor Microenvironment to Battle Cancer
por: Bödder, Johanna, et al.
Publicado: (2021)

Conventional type 1 dendritic cells (cDC1) in cancer immunity
por: Liu, Peng, et al.
Publicado: (2023)

Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs
por: Ouaguia, Laurissa, et al.
Publicado: (2020)

Resistance to TGFβ suppression and improved anti-tumor responses in CD8(+) T cells lacking PTPN22
por: Brownlie, Rebecca J., et al.
Publicado: (2017)

cDC1 dysregulation in cancer: An opportunity for intervention
por: Gajewski, Thomas F., et al.
Publicado: (2020)

Protein tyrosine phosphatase PTPN22 +1858C/T polymorphism is associated with active vitiligo
por: GARCIA-MELENDEZ, MARTHA ELENA, et al.
Publicado: (2014)

Association of Functional Polymorphism in Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Gene with Vitiligo
por: Huraib, Ghaleb Bin, et al.
Publicado: (2020)

The Tyrosine Phosphatase Activity of PTPN22 Is Involved in T Cell Development via the Regulation of TCR Expression
por: Bai, Bin, et al.
Publicado: (2023)

A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2)
por: Duval, Romain, et al.
Publicado: (2015)

cDC1 are required for the initiation of collagen-induced arthritis
por: Ramos, Maria Ines, et al.
Publicado: (2020)

Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
por: Gargaro, Marco, et al.
Publicado: (2022)

IL-12 from endogenous cDC1, and not vaccine DC, is required for Th1 induction
por: Ashour, DiyaaElDin, et al.
Publicado: (2020)

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity
por: Genera, Mariano, et al.
Publicado: (2023)

The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) R620W Functional Polymorphism in Psoriasis
por: Bin Huraib, Ghaleb, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hdecqm5bjbp3lrbll65f3lh5e4