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Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses

Multiple Sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). We have shown that CNS-specific CD8 T cells (CNS-CD8) possess a disease suppressive function in MS and its animal model, experimental autoimmune encephalomyelitis (EAE). Previous studies have focused...

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Detalles Bibliográficos
Autores principales:	Brate, Ashley A., Boyden, Alexander W., Itani, Farah R., Pewe, Lecia L., Harty, John T., Karandikar, Nitin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065686/ https://www.ncbi.nlm.nih.gov/pubmed/32161909 http://dx.doi.org/10.1016/j.jtauto.2019.100010

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