Mitigation of Rheumatic Arthritis in a Rat Model via Transdermal Delivery of Dapoxetine HCl Amalgamated as a Nanoplatform: In vitro and in vivo Assessment

PURPOSE: Dapoxetine HCl (DH), a selective serotonin reuptake inhibitor, may be useful for the treatment of rheumatic arthritis (RA). The purpose of this study was to investigate the therapeutic efficacy of transdermal delivery of DH in transethosome nanovesicles (TENVs). This novel delivery of DH ma...

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Detalles Bibliográficos
Autores principales: Salem, Heba Farouk, Nafady, Mohamed Mahmoud, Kharshoum, Rasha Mostafa, Abd el-Ghafar, Omnia Ahmed, Farouk, Hanan Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065716/
https://www.ncbi.nlm.nih.gov/pubmed/32189966
http://dx.doi.org/10.2147/IJN.S238709

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