Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs

The Wnt/β-catenin signaling pathway has been implicated in human proliferative diseases such as cancer and fibrosis. The functions of β-catenin and several other components of this pathway have been investigated in fibrosis. However, the potential role of R-spondin proteins (RSPOs), enhancers of the...

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Detalles Bibliográficos
Autores principales: Zhang, Mingjun, Haughey, Michael, Wang, Nai-Yu, Blease, Kate, Kapoun, Ann M., Couto, Suzana, Belka, Igor, Hoey, Timothy, Groza, Matthew, Hartke, James, Bennett, Brydon, Cain, Jennifer, Gurney, Austin, Benish, Brent, Castiglioni, Paola, Drew, Clifton, Lachowicz, Jean, Carayannopoulos, Leon, Nathan, Steven D., Distler, Jorg, Brenner, David A., Hariharan, Kandasamy, Cho, Ho, Xie, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065809/
https://www.ncbi.nlm.nih.gov/pubmed/32160239
http://dx.doi.org/10.1371/journal.pone.0229445

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