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Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein

The glycoproteins of hepatitis C virus, E1E2, are unlike any other viral fusion machinery yet described, and are the current focus of immunogen design in HCV vaccine development; thus, making E1E2 both scientifically and medically important. We used pre-existing, but fragmentary, structures to model...

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Detalles Bibliográficos
Autores principales:	Stejskal, Lenka, Lees, William D., Moss, David S., Palor, Machaela, Bingham, Richard J., Shepherd, Adrian J., Grove, Joe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065822/ https://www.ncbi.nlm.nih.gov/pubmed/32109245 http://dx.doi.org/10.1371/journal.pcbi.1007710

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