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Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight
Expressed in the small intestine, retinol-binding protein 2 (RBP2) facilitates dietary retinoid absorption. Rbp2-deficient (Rbp2(−/−)) mice fed a chow diet exhibit by 6-7 months-of-age higher body weights, impaired glucose metabolism, and greater hepatic triglyceride levels compared to controls. The...
Autores principales: | Lee, Seung-Ah, Yang, Kryscilla Jian Zhang, Brun, Pierre-Jacques, Silvaroli, Josie A., Yuen, Jason J., Shmarakov, Igor, Jiang, Hongfeng, Feranil, Jun B., Li, Xueting, Lackey, Atreju I., Krężel, Wojciech, Leibel, Rudolph L., Libien, Jenny, Storch, Judith, Golczak, Marcin, Blaner, William S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065888/ https://www.ncbi.nlm.nih.gov/pubmed/32195347 http://dx.doi.org/10.1126/sciadv.aay8937 |
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